5JHN

Structure of G9a SET-domain with Histone H3K9Ala mutant peptide and bound S-adenosylmethionine

Summary for 5JHN

Entry DOI	10.2210/pdb5jhn/pdb
Related	5JIN 5JIY 5JJ0
Descriptor	Histone-lysine N-methyltransferase EHMT2, Histone H3.1 peptide with K9A mutation, ZINC ION, ... (5 entities in total)
Functional Keywords	set-domain, histone methyl transferase, histone peptide, transferase
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : Q96KQ7
Total number of polymer chains	4
Total formula weight	66802.29
Authors	Jayaram, H.,Bellon, S.F.,Poy, F. (deposition date: 2016-04-21, release date: 2016-07-06, Last modification date: 2024-03-06)
Primary citation	Jayaram, H.,Hoelper, D.,Jain, S.U.,Cantone, N.,Lundgren, S.M.,Poy, F.,Allis, C.D.,Cummings, R.,Bellon, S.,Lewis, P.W. S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3. Proc.Natl.Acad.Sci.USA, 113:6182-6187, 2016 Cited by PubMed: 27185940 DOI: 10.1073/pnas.1605523113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation