5JFG
Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA
Summary for 5JFG
| Entry DOI | 10.2210/pdb5jfg/pdb |
| Descriptor | DNA repair and recombination protein RadA, PEPTIDE FHTA, DIMETHYL SULFOXIDE, ... (5 entities in total) |
| Functional Keywords | dna repair, fragment based drug design, humanisation, hydrolase |
| Biological source | Pyrococcus furiosus More |
| Total number of polymer chains | 2 |
| Total formula weight | 26172.94 |
| Authors | Fischer, G.,Marsh, M.,Moschetti, T.,Sharpe, T.,Scott, D.,Morgan, M.,Ng, H.,Skidmore, J.,Venkitaraman, A.,Abell, C.,Blundell, T.L.,Hyvonen, M. (deposition date: 2016-04-19, release date: 2016-10-26, Last modification date: 2023-03-29) |
| Primary citation | Moschetti, T.,Sharpe, T.,Fischer, G.,Marsh, M.E.,Ng, H.K.,Morgan, M.,Scott, D.E.,Blundell, T.L.,R Venkitaraman, A.,Skidmore, J.,Abell, C.,Hyvonen, M. Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428:4589-4607, 2016 Cited by PubMed: 27725183DOI: 10.1016/j.jmb.2016.10.009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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