5JED

Apo-structure of humanised RadA-mutant humRadA28

Summary for 5JED

Entry DOI	10.2210/pdb5jed/pdb
Descriptor	DNA repair and recombination protein RadA, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
Functional Keywords	dna repair, fragment based drug design, humanisation, hydrolase
Biological source	Pyrococcus furiosus
Total number of polymer chains	1
Total formula weight	25996.04
Authors	Fischer, G.,Marsh, M.,Moschetti, T.,Sharpe, T.,Scott, D.,Morgan, M.,Ng, H.,Skidmore, J.,Venkitaraman, A.,Abell, C.,Blundell, T.L.,Hyvonen, M. (deposition date: 2016-04-18, release date: 2016-10-19, Last modification date: 2024-02-07)
Primary citation	Moschetti, T.,Sharpe, T.,Fischer, G.,Marsh, M.E.,Ng, H.K.,Morgan, M.,Scott, D.E.,Blundell, T.L.,R Venkitaraman, A.,Skidmore, J.,Abell, C.,Hyvonen, M. Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428:4589-4607, 2016 Cited by PubMed: 27725183 DOI: 10.1016/j.jmb.2016.10.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.332 Å)

Structure validation