5H5K

ATP and CMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5H5K

• Entry DOI: 10.2210/pdb5h5k/pdb
• Related: 2PBR 5H56 5H5B
• Descriptor: Thymidylate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: kinase, tranferase, complex, nucleotide binding, transferase
• Biological source: Aquifex aeolicus (strain VF5)
• Total number of polymer chains: 2
• Total formula weight: 46701.49

Authors

Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2016-11-06, release date: 2017-06-28, Last modification date: 2023-11-08)

• Primary citation: Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.; Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate; FEBS J., 284:2527-2544, 2017; PubMed: 28627020; DOI: 10.1111/febs.14140

Experimental method

X-RAY DIFFRACTION (2.3 Å)