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5H56

ADP and dTDP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5H56
Entry DOI10.2210/pdb5h56/pdb
Related5H5B 5H5K
DescriptorThymidylate kinase, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywordskinase, transferase, rossmann fold, product-bound
Biological sourceAquifex aeolicus (strain VF5)
Total number of polymer chains2
Total formula weight46927.03
Authors
Biswas, A.,Jeyakanthan, J.,Sekar, K.,Kuramitsu, S.,Yokoyama, S. (deposition date: 2016-11-04, release date: 2017-06-28, Last modification date: 2023-11-08)
Primary citationBiswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.
Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate
FEBS J., 284:2527-2544, 2017
Cited by
PubMed: 28627020
DOI: 10.1111/febs.14140
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

건을2024-03-27부터공개중

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