5H1I

NMR structure of TIBA, a chimera of SFTI

Summary for 5H1I

• Entry DOI: 10.2210/pdb5h1i/pdb
• Related: 5H1H
• NMR Information: BMRB: 36024
• Descriptor: Bradykinin-trypsin inhibitor secondary loop chimera (1 entity in total)
• Functional Keywords: tiba, chimera, sunflower trypsin inhibitor, cyclic peptide, de novo protein
• Biological source: Helianthus annuus
• Total number of polymer chains: 1
• Total formula weight: 1944.39

Authors

Xiao, T.,Tam, J.P. (deposition date: 2016-10-10, release date: 2017-04-19, Last modification date: 2023-06-14)

• Primary citation: Qiu, Y.,Taichi, M.,Wei, N.,Yang, H.,Luo, K.Q.,Tam, J.P.; An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor.; J. Med. Chem., 60:504-510, 2017; PubMed: 27977181; DOI: 10.1021/acs.jmedchem.6b01011

Experimental method

SOLUTION NMR