5GZB

Crystal Structure of Transcription Factor TEAD4 in Complex with M-CAT DNA

Summary for 5GZB

• Entry DOI: 10.2210/pdb5gzb/pdb
• Descriptor: Transcriptional enhancer factor TEF-3, DNA (5'-D(*TP*TP*GP*CP*AP*TP*TP*CP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*TP*GP*CP*AP*A)-3'), ... (6 entities in total)
• Functional Keywords: transcription factor, dna, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q15561
• Total number of polymer chains: 3
• Total formula weight: 20415.83

Authors

He, F.,Shi, Z.B.,Zhou, Z.C. (deposition date: 2016-09-28, release date: 2017-04-19, Last modification date: 2017-08-09)

• Primary citation: Shi, Z.B.,He, F.,Chen, M.,Hua, L.,Wang, W.,Jiao, S.,Zhou, Z.C.; DNA-binding mechanism of the Hippo pathway transcription factor TEAD4; Oncogene, 36:4362-4369, 2017; PubMed: 28368398; DOI: 10.1038/onc.2017.24

Experimental method

X-RAY DIFFRACTION (2.704 Å)