5GRG

Crystal structure of dual peptide from EBV in complex with HLA-A*11:01

Summary for 5GRG

• Entry DOI: 10.2210/pdb5grg/pdb
• Related: 5GRD
• Descriptor: HLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, Epstein Barr Virus, Latent Membrane Protein 2 epitope, ... (6 entities in total)
• Functional Keywords: immune system, human leukocyte antigen
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P13746; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 4
• Total formula weight: 44988.74

Authors

Tadwal, V.S.,Xiao, Z.,Ren, E.C. (deposition date: 2016-08-11, release date: 2017-08-09, Last modification date: 2023-11-08)

• Primary citation: Xiao, Z.,Ye, Z.,Tadwal, V.S.,Shen, M.,Ren, E.C.; Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens; Sci Rep, 7:5072-5072, 2017; PubMed: 28698575; DOI: 10.1038/s41598-017-05171-w

Experimental method

X-RAY DIFFRACTION (1.94 Å)