5GNL
Cytochrome P450 Vdh (CYP107BR1) F106V mutant
Summary for 5GNL
| Entry DOI | 10.2210/pdb5gnl/pdb |
| Related | 5GNM |
| Descriptor | Vitamin D(3) 25-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, 2-(2-METHOXYETHOXY)ETHANOL, ... (4 entities in total) |
| Functional Keywords | oxidoreductase, cytochrome p450 |
| Biological source | Pseudonocardia autotrophica (Amycolata autotrophica) |
| Cellular location | Cytoplasm : C4B644 |
| Total number of polymer chains | 1 |
| Total formula weight | 46176.20 |
| Authors | Yasutake, Y.,Tamura, T. (deposition date: 2016-07-22, release date: 2017-05-17, Last modification date: 2023-11-08) |
| Primary citation | Yasutake, Y.,Kameda, T.,Tamura, T. Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site Acta Crystallogr F Struct Biol Commun, 73:266-275, 2017 Cited by PubMed: 28471358DOI: 10.1107/S2053230X17004782 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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