5FZY

CRYSTAL STRUCTURE OF N19D POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR OF SERINE AND ASPARTIC PROTEASES IN SPACE GROUP C2221 AND PH 3.5

Summary for 5FZY

Entry DOI	10.2210/pdb5fzy/pdb
Related	5FZU 5FZZ 5G00
Descriptor	KTI-A PROTEIN (2 entities in total)
Functional Keywords	hydrolase, sti-kunitz inhibitor, aspartic proteases, serine proteases, protease inhibitor, bi-functional protease inhibitor, hydrolase inhibitor, kunitz-type inhibitor
Biological source	SOLANUM TUBEROSUM (POTATO)
Total number of polymer chains	2
Total formula weight	41054.98
Authors	Guerra, Y.,Rudino-Pinera, E. (deposition date: 2016-03-15, release date: 2016-07-06, Last modification date: 2024-01-10)
Primary citation	Guerra, Y.,Valiente, P.A.,Pons, T.,Berry, C.,Rudino-Pinera, E. Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop? J. Struct. Biol., 195:259-271, 2016 Cited by PubMed: 27329566 DOI: 10.1016/j.jsb.2016.06.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.47 Å)

Structure validation