5FBT

Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin

Summary for 5FBT

Entry DOI	10.2210/pdb5fbt/pdb
Related	5FBS 5FBU
Descriptor	Phosphoenolpyruvate synthase, Rifampin, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	antibiotic resistance, rifamycins, rifampin, phosphotransferase, atp grasp domain, phosphohistidine domain, structural genomics, center for structural genomics of infectious diseases, csgid, transferase-antibiotic complex, transferase/antibiotic
Biological source	Listeria monocytogenes serotype 4b str. F2365
Total number of polymer chains	1
Total formula weight	99012.50
Authors	Stogios, P.J.,Wawrzak, Z.,Skarina, T.,Yim, V.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-12-14, release date: 2015-12-30, Last modification date: 2024-01-31)
Primary citation	Stogios, P.J.,Cox, G.,Spanogiannopoulos, P.,Pillon, M.C.,Waglechner, N.,Skarina, T.,Koteva, K.,Guarne, A.,Savchenko, A.,Wright, G.D. Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7:11343-11343, 2016 Cited by PubMed: 27103605 DOI: 10.1038/ncomms11343 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.702 Å)

Structure validation