5EZ0
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA.
Summary for 5EZ0
Entry DOI | 10.2210/pdb5ez0/pdb |
Related | 3NFK 3NFL 5EYZ |
Descriptor | Tyrosine-protein phosphatase non-receptor type 4, Mitogen-activated protein kinase 12, SULFATE ION, ... (4 entities in total) |
Functional Keywords | apoptosis, cell death, glioblastoma, multiprotein complexes, pdz domains, p38gamma, mitogen activated protein kinase, protein binding, non-receptor type 4, ptpn4, rabies virus, pdz binding motif |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P29074 |
Total number of polymer chains | 8 |
Total formula weight | 52071.39 |
Authors | Maisonneuve, P.,Vaney, M.C.,Caillet-Saguy, C.,Lafon, M.,Delepierre, M.,Cordier, F.,Wolff, N. (deposition date: 2015-11-26, release date: 2016-06-08, Last modification date: 2024-01-10) |
Primary citation | Maisonneuve, P.,Caillet-Saguy, C.,Vaney, M.C.,Bibi-Zainab, E.,Sawyer, K.,Raynal, B.,Haouz, A.,Delepierre, M.,Lafon, M.,Cordier, F.,Wolff, N. Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291:16699-16708, 2016 Cited by PubMed: 27246854DOI: 10.1074/jbc.M115.707208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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