5EXH

Crystal structure of mTET3-CXXC domain in complex with 5-carboxylcytosine DNA at 1.3 Angstroms resolution.

Summary for 5EXH

• Entry DOI: 10.2210/pdb5exh/pdb
• Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*(1CC)P*GP*GP*AP*TP*TP*C)-3'), Methylcytosine dioxygenase TET3, ZINC ION, ... (4 entities in total)
• Functional Keywords: mouse tet3, complex, 5-carboxylcytosine, reader, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 13045.29

Authors

Song, J. (deposition date: 2015-11-23, release date: 2016-02-03, Last modification date: 2023-09-27)

• Primary citation: Jin, S.G.,Zhang, Z.M.,Dunwell, T.L.,Harter, M.R.,Wu, X.,Johnson, J.,Li, Z.,Liu, J.,Szabo, P.E.,Lu, Q.,Xu, G.L.,Song, J.,Pfeifer, G.P.; Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration.; Cell Rep, 14:493-505, 2016; PubMed: 26774490; DOI: 10.1016/j.celrep.2015.12.044

Experimental method

X-RAY DIFFRACTION (1.3 Å)