5EDM
Crystal structure of prothrombin deletion mutant residues 154-167 ( Form I )
Summary for 5EDM
| Entry DOI | 10.2210/pdb5edm/pdb |
| Related | 4O03 |
| Descriptor | Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | prothrombin, kringle, protease, coagulation factor, enzyme mechanism, kinetics, structure-function, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 67011.68 |
| Authors | Pozzi, N.,Chen, Z.,Di Cera, E. (deposition date: 2015-10-21, release date: 2016-01-20, Last modification date: 2023-11-15) |
| Primary citation | Pozzi, N.,Chen, Z.,Di Cera, E. How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin. J.Biol.Chem., 291:6071-6082, 2016 Cited by PubMed: 26763231DOI: 10.1074/jbc.M115.700401 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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