5E94

Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain

Summary for 5E94

• Entry DOI: 10.2210/pdb5e94/pdb
• Descriptor: Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, Glucagon-like peptide 1 receptor, ... (4 entities in total)
• Functional Keywords: antibody antagonist glp-1 receptor, immune system, membrane protein
• Biological source: Mus musculus (House Mouse); More
• Cellular location: Cell membrane ; Multi- pass membrane protein : P43220
• Total number of polymer chains: 6
• Total formula weight: 125380.77

Authors

Soroka, V.,Schluckebier, G.,Reedtz-Runge, S. (deposition date: 2015-10-14, release date: 2016-08-24, Last modification date: 2024-01-10)

• Primary citation: Hennen, S.,Kodra, J.T.,Soroka, V.,Krogh, B.O.,Wu, X.,Kaastrup, P.,Orskov, C.,Ronn, S.G.,Schluckebier, G.,Barbateskovic, S.,Gandhi, P.S.,Reedtz-Runge, S.; Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.; Sci Rep, 6:26236-26236, 2016; PubMed: 27196125; DOI: 10.1038/srep26236

Experimental method

X-RAY DIFFRACTION (2 Å)