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5E0V

Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms

Summary for 5E0V
Entry DOI10.2210/pdb5e0v/pdb
Related1AXC 5E0T 5E0U
DescriptorProliferating cell nuclear antigen, Flap endonuclease 1 (3 entities in total)
Functional Keywordsdna replication, sliding clamp, dna binding protein
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus : P12004
Mitochondrion . Nucleus, nucleolus : B4DWZ4
Total number of polymer chains4
Total formula weight61189.57
Authors
Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. (deposition date: 2015-09-29, release date: 2016-04-20, Last modification date: 2023-09-27)
Primary citationDuffy, C.M.,Hilbert, B.J.,Kelch, B.A.
A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428:1023-1040, 2016
Cited by
PubMed: 26688547
DOI: 10.1016/j.jmb.2015.11.029
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.074 Å)
Structure validation

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