5DPX

1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.

Summary for 5DPX

Entry DOI	10.2210/pdb5dpx/pdb
Related	2FM6 2FU7 2FU8 2FU9 2GFJ 2GFK 2HB9
Descriptor	Metallo-beta-lactamase L1 type 3, ZINC ION, 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, ... (5 entities in total)
Functional Keywords	hydrolase, metallo, zn, lactamase
Biological source	Stenotrophomonas maltophilia (Pseudomonas maltophilia)
Cellular location	Periplasm : P52700
Total number of polymer chains	2
Total formula weight	58505.27
Authors	Nauton, L.,Garau, G.,Khan, R.,Dideberg, O. (deposition date: 2015-09-14, release date: 2017-01-11, Last modification date: 2024-01-10)
Primary citation	Sevaille, L.,Gavara, L.,Bebrone, C.,De Luca, F.,Nauton, L.,Achard, M.,Mercuri, P.,Tanfoni, S.,Borgianni, L.,Guyon, C.,Lonjon, P.,Turan-Zitouni, G.,Dzieciolowski, J.,Becker, K.,Benard, L.,Condon, C.,Maillard, L.,Martinez, J.,Frere, J.M.,Dideberg, O.,Galleni, M.,Docquier, J.D.,Hernandez, J.F. 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases. ChemMedChem, 12:972-985, 2017 Cited by PubMed: 28505394 DOI: 10.1002/cmdc.201700186 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation