5DO2

Complex structure of MERS-RBD bound with 4C2 antibody

Summary for 5DO2

• Entry DOI: 10.2210/pdb5do2/pdb
• Related: 4KR0
• Descriptor: S protein, 4C2 heavy chain, 4C2 light chain, ... (5 entities in total)
• Functional Keywords: receptor-binding domain of mers-cov spike, 4c2 antibody, neuralization, receptor-binding blocking., viral protein-immune system complex, viral protein/immune system
• Biological source: Middle East respiratory syndrome coronavirus; More
• Total number of polymer chains: 6
• Total formula weight: 149787.68

Authors

Li, Y.,Wan, Y.,Liu, P.,Zhao, J.,Lu, G.,Qi, J.,Wang, Q.,Lu, X.,Wu, Y.,Liu, W.,Yuen, K.Y.,Perlman, S.,Gao, G.F.,Yan, J. (deposition date: 2015-09-10, release date: 2015-10-14, Last modification date: 2023-11-08)

• Primary citation: Li, Y.,Wan, Y.,Liu, P.,Zhao, J.,Lu, G.,Qi, J.,Wang, Q.,Lu, X.,Wu, Y.,Liu, W.,Zhang, B.,Yuen, K.Y.,Perlman, S.,Gao, G.F.,Yan, J.; A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.; Cell Res., 25:1237-1249, 2015; PubMed: 26391698; DOI: 10.1038/cr.2015.113

Experimental method

X-RAY DIFFRACTION (2.409 Å)