5DD1

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques

Summary for 5DD1

• Entry DOI: 10.2210/pdb5dd1/pdb
• Related: 5DD0 5DD3 5DD5 5DD6
• Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN (3 entities in total)
• Functional Keywords: hiv hiv-1 gp41 mper antibody, immune system
• Biological source: Macaca mulatta; More
• Total number of polymer chains: 2
• Total formula weight: 47859.23

Authors

Zhang, R.,Verkoczy, L.,Wiehe, K.,Alam, S.M.,Nicely, N.I.,Santra, S.,Bradley, T.,Pemble, C.,Gao, F.,Montefiori, D.C.,Bouton-Verville, H.,Kelsoe, G.,Parks, R.,Foulger, A.,Tomaras, G.,Keple, T.B.,Moody, M.A.,Liao, H.-X.,Haynes, B.F. (deposition date: 2015-08-24, release date: 2016-05-11, Last modification date: 2023-09-27)

• Primary citation: Zhang, R.,Verkoczy, L.,Wiehe, K.,Munir Alam, S.,Nicely, N.I.,Santra, S.,Bradley, T.,Pemble, C.W.,Zhang, J.,Gao, F.,Montefiori, D.C.,Bouton-Verville, H.,Kelsoe, G.,Larimore, K.,Greenberg, P.D.,Parks, R.,Foulger, A.,Peel, J.N.,Luo, K.,Lu, X.,Trama, A.M.,Vandergrift, N.,Tomaras, G.D.,Kepler, T.B.,Moody, M.A.,Liao, H.X.,Haynes, B.F.; Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.; Sci Transl Med, 8:336ra62-336ra62, 2016; PubMed: 27122615; DOI: 10.1126/scitranslmed.aaf0618

Experimental method

X-RAY DIFFRACTION (1.597 Å)