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5CU8

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)

Summary for 5CU8
Entry DOI10.2210/pdb5cu8/pdb
DescriptorBromodomain adjacent to zinc finger domain protein 2B, 6-chloro-1,3-benzothiazol-2-amine, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q9UIF8
Total number of polymer chains1
Total formula weight13863.80
Authors
Primary citationBradley, A.,Pearce, N.,Krojer, T.,Ng, J.,Talon, R.,Vollmar, M.,Jose, B.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC)
Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)
To be published,
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

數據於2024-03-27公開中

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