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5CP6

Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]

Summary for 5CP6
Entry DOI10.2210/pdb5cp6/pdb
DescriptorDNA (145-MER), Histone H3.2, Histone H4, ... (10 entities in total)
Functional Keywordsnucleosome core particle, antitumour compound, structural protein-dna complex, structural protein/dna
Biological sourceXenopus laevis (African clawed frog)
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Cellular locationNucleus: P84233 P62799 P02281
Total number of polymer chains10
Total formula weight199584.29
Authors
Ma, Z.,Adhireksan, Z.,Murray, B.S.,Dyson, P.J.,Davey, C.A. (deposition date: 2015-07-21, release date: 2016-06-01, Last modification date: 2023-11-08)
Primary citationMa, Z.,Palermo, G.,Adhireksan, Z.,Murray, B.S.,von Erlach, T.,Dyson, P.J.,Rothlisberger, U.,Davey, C.A.
An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55:7441-7444, 2016
Cited by
PubMed: 27184539
DOI: 10.1002/anie.201602145
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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