5CNO
Crystal structure of the EGFR kinase domain mutant V924R
Summary for 5CNO
Entry DOI | 10.2210/pdb5cno/pdb |
Related | 5CNN |
Descriptor | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | kinase egfr, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 113925.57 |
Authors | Kovacs, E.,Das, R.,Mirza, A.,Jura, N.,Barros, T.,Kuriyan, J. (deposition date: 2015-07-17, release date: 2015-07-29, Last modification date: 2024-03-06) |
Primary citation | Kovacs, E.,Das, R.,Wang, Q.,Collier, T.S.,Cantor, A.,Huang, Y.,Wong, K.,Mirza, A.,Barros, T.,Grob, P.,Jura, N.,Bose, R.,Kuriyan, J. Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol.Cell.Biol., 35:3083-3102, 2015 Cited by PubMed: 26124280DOI: 10.1128/MCB.00248-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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