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5CNO

Crystal structure of the EGFR kinase domain mutant V924R

Summary for 5CNO
Entry DOI10.2210/pdb5cno/pdb
Related5CNN
DescriptorEpidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordskinase egfr, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total formula weight113925.57
Authors
Kovacs, E.,Das, R.,Mirza, A.,Jura, N.,Barros, T.,Kuriyan, J. (deposition date: 2015-07-17, release date: 2015-07-29, Last modification date: 2024-03-06)
Primary citationKovacs, E.,Das, R.,Wang, Q.,Collier, T.S.,Cantor, A.,Huang, Y.,Wong, K.,Mirza, A.,Barros, T.,Grob, P.,Jura, N.,Bose, R.,Kuriyan, J.
Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.
Mol.Cell.Biol., 35:3083-3102, 2015
Cited by
PubMed: 26124280
DOI: 10.1128/MCB.00248-15
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

217705

數據於2024-03-27公開中

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