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5CBE

E10 in complex with CXCL13

Summary for 5CBE
Entry DOI10.2210/pdb5cbe/pdb
Related5C2B 5C6W 5CBA
DescriptorE10 heavy chain, E10 light chain, C-X-C motif chemokine 13, ... (5 entities in total)
Functional Keywordsanti-cxcl13, e10, scfv, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight76013.07
Authors
Tu, C.,Bard, J.,Mosyak, L. (deposition date: 2015-06-30, release date: 2015-11-04, Last modification date: 2023-09-27)
Primary citationTu, C.,Terraube, V.,Tam, A.S.,Stochaj, W.,Fennell, B.J.,Lin, L.,Stahl, M.,LaVallie, E.R.,Somers, W.,Finlay, W.J.,Mosyak, L.,Bard, J.,Cunningham, O.
A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
J. Biol. Chem., 291:1267-1276, 2016
Cited by
PubMed: 26515064
DOI: 10.1074/jbc.M115.688010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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