5BRW

Catalytic Improvement of an Artificial Metalloenzyme by Computational Design

Summary for 5BRW

Entry DOI	10.2210/pdb5brw/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	artificial metalloenzyme, lyase, imine reductase, transfer hydrogenase, oxidoreductase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29667.75
Authors	Heinisch, T.,Pellizzoni, M.,Duerrenberger, M.,Tinberg, C.E.,Koehler, V.,Klehr, J.,Haeussinger, D.,Baker, D.,Ward, T.R. (deposition date: 2015-06-01, release date: 2015-06-17, Last modification date: 2024-01-10)
Primary citation	Heinisch, T.,Pellizzoni, M.,Durrenberger, M.,Tinberg, C.E.,Kohler, V.,Klehr, J.,Haussinger, D.,Baker, D.,Ward, T.R. Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. J.Am.Chem.Soc., 137:10414-10419, 2015 Cited by PubMed: 26226626 DOI: 10.1021/jacs.5b06622 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation