5BPQ
Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form II
Summary for 5BPQ
| Entry DOI | 10.2210/pdb5bpq/pdb |
| Descriptor | Frizzled-4, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | wnt signalling pathway, glycoprotein, g protein coupled receptor, receptor for norrin recognition, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 67741.21 |
| Authors | Chang, T.-H.,Hsieh, F.-L.,Harlos, K.,Jones, E.Y. (deposition date: 2015-05-28, release date: 2015-07-01, Last modification date: 2024-01-10) |
| Primary citation | Chang, T.H.,Hsieh, F.L.,Zebisch, M.,Harlos, K.,Elegheert, J.,Jones, E.Y. Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4:e06554-, 2015 Cited by PubMed: 26158506DOI: 10.7554/eLife.06554 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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