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5BMV

CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX

Summary for 5BMV
Entry DOI10.2210/pdb5bmv/pdb
DescriptorTubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, ... (13 entities in total)
Functional Keywordscomplex, structural protein
Biological sourceRattus norvegicus (Rat)
More
Cellular locationCytoplasm, cytoskeleton: P81947 P02554
Golgi apparatus : P63043
Total number of polymer chains6
Total formula weight265948.62
Authors
Wang, Y.,Chen, Q.,Zhang, R. (deposition date: 2015-05-23, release date: 2016-07-13, Last modification date: 2023-11-08)
Primary citationWang, Y.,Benz, F.W.,Wu, Y.,Wang, Q.,Chen, Y.,Chen, X.,Li, H.,Zhang, Y.,Zhang, R.,Yang, J.
Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89:233-242, 2016
Cited by
PubMed: 26660762
DOI: 10.1124/mol.115.100149
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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