5AWX
Crystal structure of Human PTPRZ D1 domain
Summary for 5AWX
| Entry DOI | 10.2210/pdb5awx/pdb |
| Descriptor | Receptor-type tyrosine-protein phosphatase zeta, BROMIDE ION (3 entities in total) |
| Functional Keywords | protein tyrosine phosphatase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted : P23471 |
| Total number of polymer chains | 1 |
| Total formula weight | 34274.02 |
| Authors | Sugawara, H. (deposition date: 2015-07-10, release date: 2016-02-17, Last modification date: 2023-11-08) |
| Primary citation | Fujikawa, A.,Nagahira, A.,Sugawara, H.,Ishii, K.,Imajo, S.,Matsumoto, M.,Kuboyama, K.,Suzuki, R.,Tanga, N.,Noda, M.,Uchiyama, S.,Tomoo, T.,Ogata, A.,Masumura, M.,Noda, M. Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma Sci Rep, 6:20473-20473, 2016 Cited by PubMed: 26857455DOI: 10.1038/srep20473 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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