5AQE

Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase

5AQE の概要

• エントリーDOI: 10.2210/pdb5aqe/pdb
• 分子名称: SUBTILISIN SAVINASE, (4-VINYLPHENYL)METHANESULFONIC ACID, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: hydrolase, protease, subtilisin, catalysis, palladium, metalloenzyme, heck reaction, cross-coupling
• 由来する生物種: BACILLUS LENTUS
• 細胞内の位置: Secreted: P29600
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27272.40

構造登録者

Sharma, M.,Diaz-Rodriguez, A.,Offen, W.A.,Palm-Espling, M.E.,Pordea, A.,Wormald, M.R.,Mcdonough, M.,Davies, G.J.,Davis, B.G. (登録日: 2015-09-22, 公開日: 2015-10-07, 最終更新日: 2024-01-10)

• 主引用文献: Sharma, M.,Diaz-Rodriguez, A.,Offen, W.A.,Pordea, A.,Wormald, M.R.,Mcdonough, M.,Davies, G.J.,Davis, B.G.; Bisubstrate Localisation by a Tailored Serine Protease Allows Creation of a Heck-Ase; To be Published,

実験手法

X-RAY DIFFRACTION (1.1 Å)