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5A7S

Crystal structure of human JMJD2A in complex with compound 44

Summary for 5A7S
Entry DOI10.2210/pdb5a7s/pdb
Related5A7N 5A7O 5A7P 5A7Q 5A7W 5A80
DescriptorLYSINE-SPECIFIC DEMETHYLASE 4A, MANGANESE (II) ION, ZINC ION, ... (7 entities in total)
Functional Keywordsoxidoreductase, jmjd2a, kdm4a
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus : O75164
Total number of polymer chains2
Total formula weight90525.04
Authors
Primary citationKorczynska, M.,Le, D.D.,Younger, N.,Gregori-Puigjane, E.,Tumber, A.,Krojer, T.,Velupillai, S.,Gileadi, C.,Nowak, R.P.,Iwasa, E.,Pollock, S.B.,Ortiz Torres, I.,Oppermann, U.,Shoichet, B.K.,Fujimori, D.G.
Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors.
J.Med.Chem., 59:1580-, 2016
Cited by
PubMed: 26699912
DOI: 10.1021/ACS.JMEDCHEM.5B01527
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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