5SYJ

Crystal structure of the D141A variant of B. pseudomallei KatGin complex with isoniazid

Replaces:  4KWQ

Summary for 5SYJ

• Entry DOI: 10.2210/pdb5syj/pdb
• Descriptor: Catalase-peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... (8 entities in total)
• Functional Keywords: katg, catalase-peroxidase, oxidoreductase, isoniazid
• Biological source: Burkholderia pseudomallei (strain 1710b)
• Total number of polymer chains: 2
• Total formula weight: 162019.70

Authors

Loewen, P.C. (deposition date: 2016-08-11, release date: 2016-09-21, Last modification date: 2023-10-04)

• Primary citation: Vidossich, P.,Loewen, P.C.,Carpena, X.,Fiorin, G.,Fita, I.,Rovira, C.; Binding of the antitubercular pro-drug isoniazid in the heme access channel of catalase-peroxidase (KatG). A combined structural and metadynamics investigation.; J Phys Chem B, 118:2924-2931, 2014; PubMed: 24568093; DOI: 10.1021/jp4123425

Experimental method

X-RAY DIFFRACTION (1.88 Å)