5OYJ
Crystal structure of VEGFR-2 domains 4-5 in complex with DARPin D4b
Summary for 5OYJ
Entry DOI | 10.2210/pdb5oyj/pdb |
Related PRD ID | PRD_900006 |
Descriptor | DARPin D4b, Vascular endothelial growth factor receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | glycoprotein receptor kinase designed ankyrin repeat protein angiogenesis, signaling protein |
Biological source | synthetic construct More |
Total number of polymer chains | 4 |
Total formula weight | 93563.33 |
Authors | Piscitelli, C.L.,Thieltges, K.M.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K. (deposition date: 2017-09-10, release date: 2018-03-14, Last modification date: 2024-01-17) |
Primary citation | Thieltges, K.M.,Avramovic, D.,Piscitelli, C.L.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K. Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling. Angiogenesis, 21:533-543, 2018 Cited by PubMed: 29502220DOI: 10.1007/s10456-018-9606-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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