5OUG
Humanized alpha-AChBP (acetylcholine binding protein) in complex with lobeline and allosteric binder fragment 4.
Summary for 5OUG
Entry DOI | 10.2210/pdb5oug/pdb |
Related | 5afm |
Descriptor | Humanized alpha-AChBP, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | acetylcholine binding protein, nicotinic acetylcholine receptor, choline-binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 5 |
Total formula weight | 127198.39 |
Authors | Delbart, F.,Gruss, F.,Ulens, C. (deposition date: 2017-08-23, release date: 2017-12-20, Last modification date: 2020-07-29) |
Primary citation | Delbart, F.,Brams, M.,Gruss, F.,Noppen, S.,Peigneur, S.,Boland, S.,Chaltin, P.,Brandao-Neto, J.,von Delft, F.,Touw, W.G.,Joosten, R.P.,Liekens, S.,Tytgat, J.,Ulens, C. An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein. J. Biol. Chem., 293:2534-2545, 2018 Cited by PubMed: 29237730DOI: 10.1074/jbc.M117.815316 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.57 Å) |
Structure validation
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