5N9X

Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, ligand bound structure

Replaces:  5APB

Summary for 5N9X

• Entry DOI: 10.2210/pdb5n9x/pdb
• Related: 5N9W
• Descriptor: Adenylation domain, THREONINE, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: adenylation domain, substrate specificity, non-ribosomal code, threonine adenylate, ligase
• Biological source: Streptomyces sp.
• Total number of polymer chains: 2
• Total formula weight: 116548.81

Authors

Savino, C.,Vallone, B.,Scaglione, A.,Parisi, G.,Montemiglio, L.C.,Fullone, M.R.,Grgurina, I. (deposition date: 2017-02-27, release date: 2017-07-26, Last modification date: 2024-01-17)

• Primary citation: Scaglione, A.,Fullone, M.R.,Montemiglio, L.C.,Parisi, G.,Zamparelli, C.,Vallone, B.,Savino, C.,Grgurina, I.; Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.; FEBS J., 284:2981-2999, 2017; PubMed: 28704585; DOI: 10.1111/febs.14163

Experimental method

X-RAY DIFFRACTION (2.396 Å)