5KJC

V222I horse liver alcohol dehydrogenase complexed with NAD+ and pentafluorobenzyl alcohol

Summary for 5KJC

• Entry DOI: 10.2210/pdb5kjc/pdb
• Related: 4DWV 5KCP 5KCZ 5KJ1 5KJ6 5KJE 5KJF
• Descriptor: Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
• Functional Keywords: oxidoreductase, rossmann fold, michaelis analogue, dynamics
• Biological source: Equus caballus (Horse)
• Total number of polymer chains: 2
• Total formula weight: 82310.14

Authors

Plapp, B.V. (deposition date: 2016-06-18, release date: 2016-06-29, Last modification date: 2023-09-27)

• Primary citation: Shanmuganatham, K.K.,Wallace, R.S.,Ting-I Lee, A.,Plapp, B.V.; Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis.; Protein Sci., 27:750-768, 2018; PubMed: 29271062; DOI: 10.1002/pro.3370

Experimental method

X-RAY DIFFRACTION (1.2 Å)