5KFG

Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 30s

Summary for 5KFG

• Entry DOI: 10.2210/pdb5kfg/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (9 entities in total)
• Functional Keywords: in crystallo reaction, dna polymerase, metal ion dependent catalysis, replication, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55569.11

Authors

Gao, Y.,Yang, W. (deposition date: 2016-06-12, release date: 2016-06-29, Last modification date: 2023-09-27)

• Primary citation: Gao, Y.,Yang, W.; Capture of a third Mg2+ is essential for catalyzing DNA synthesis.; Science, 352:1334-1337, 2016; PubMed: 27284197; DOI: 10.1126/science.aad9633

Experimental method

X-RAY DIFFRACTION (1.55 Å)