5IO1
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN Z ALPHA-1-ANTITRYPSIN
Summary for 5IO1
Entry DOI | 10.2210/pdb5io1/pdb |
Descriptor | Alpha-1-antitrypsin, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | serpins, acute phase, alternative splicing, blood coagulation, disease mutation, glycoprotein, hydrolase, polymorphism, protease, protease inhibitor, secreted, serine protease inhibitor, hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 90462.75 |
Authors | Zhou, A. (deposition date: 2016-03-08, release date: 2016-06-08, Last modification date: 2023-11-08) |
Primary citation | Huang, X.,Zheng, Y.,Zhang, F.,Wei, Z.,Wang, Y.,Carrell, R.W.,Read, R.J.,Chen, G.Q.,Zhou, A. Molecular Mechanism of Z alpha 1-Antitrypsin Deficiency J. Biol. Chem., 291:15674-15686, 2016 Cited by PubMed: 27246852DOI: 10.1074/jbc.M116.727826 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.34 Å) |
Structure validation
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