4ZWJ

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Summary for 4ZWJ

• Entry DOI: 10.2210/pdb4zwj/pdb
• Descriptor: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin (1 entity in total)
• Functional Keywords: gpcr, rhodopsin, visual arrestin, x-ray free electron laser, serial femtosecond crystallography, signaling protein, structural genomics, gpcr network
• Biological source: Enterobacteria phage T4; More
• Cellular location: Cell projection, cilium, photoreceptor outer segment : P20443
• Total number of polymer chains: 4
• Total formula weight: 403444.41

Authors

Kang, Y.,Zhou, X.E.,Gao, X.,He, Y.,Liu, W.,Ishchenko, A.,Barty, A.,White, T.A.,Yefanov, O.,Han, G.W.,Xu, Q.,de Waal, P.W.,Ke, J.,Tan, M.H.E.,Zhang, C.,Moeller, A.,West, G.M.,Pascal, B.,Eps, N.V.,Caro, L.N.,Vishnivetskiy, S.A.,Lee, R.J.,Suino-Powell, K.M.,Gu, X.,Pal, K.,Ma, J.,Zhi, X.,Boutet, S.,Williams, G.J.,Messerschmidt, M.,Gati, C.,Zatsepin, N.A.,Wang, D.,James, D.,Basu, S.,Roy-Chowdhury, S.,Conrad, C.,Coe, J.,Liu, H.,Lisova, S.,Kupitz, C.,Grotjohann, I.,Fromme, R.,Jiang, Y.,Tan, M.,Yang, H.,Li, J.,Wang, M.,Zheng, Z.,Li, D.,Howe, N.,Zhao, Y.,Standfuss, J.,Diederichs, K.,Dong, Y.,Potter, C.S.,Carragher, B.,Caffrey, M.,Jiang, H.,Chapman, H.N.,Spence, J.C.H.,Fromme, P.,Weierstall, U.,Ernst, O.P.,Katritch, V.,Gurevich, V.V.,Griffin, P.R.,Hubbell, W.L.,Stevens, R.C.,Cherezov, V.,Melcher, K.,Xu, H.E.,GPCR Network (GPCR) (deposition date: 2015-05-19, release date: 2015-07-29, Last modification date: 2023-09-27)

• Primary citation: Kang, Y.,Zhou, X.E.,Gao, X.,He, Y.,Liu, W.,Ishchenko, A.,Barty, A.,White, T.A.,Yefanov, O.,Han, G.W.,Xu, Q.,de Waal, P.W.,Ke, J.,Tan, M.H.,Zhang, C.,Moeller, A.,West, G.M.,Pascal, B.D.,Van Eps, N.,Caro, L.N.,Vishnivetskiy, S.A.,Lee, R.J.,Suino-Powell, K.M.,Gu, X.,Pal, K.,Ma, J.,Zhi, X.,Boutet, S.,Williams, G.J.,Messerschmidt, M.,Gati, C.,Zatsepin, N.A.,Wang, D.,James, D.,Basu, S.,Roy-Chowdhury, S.,Conrad, C.E.,Coe, J.,Liu, H.,Lisova, S.,Kupitz, C.,Grotjohann, I.,Fromme, R.,Jiang, Y.,Tan, M.,Yang, H.,Li, J.,Wang, M.,Zheng, Z.,Li, D.,Howe, N.,Zhao, Y.,Standfuss, J.,Diederichs, K.,Dong, Y.,Potter, C.S.,Carragher, B.,Caffrey, M.,Jiang, H.,Chapman, H.N.,Spence, J.C.,Fromme, P.,Weierstall, U.,Ernst, O.P.,Katritch, V.,Gurevich, V.V.,Griffin, P.R.,Hubbell, W.L.,Stevens, R.C.,Cherezov, V.,Melcher, K.,Xu, H.E.; Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.; Nature, 523:561-567, 2015; PubMed: 26200343; DOI: 10.1038/nature14656

Experimental method

X-RAY DIFFRACTION (3.302 Å)