4ZRB

Crystal Structure of Hypothetical Thioesterase Protein SP_1851 with Coenzyme A from Streptococcus pneumoniae TIGR4

4ZRB の概要

• エントリーDOI: 10.2210/pdb4zrb/pdb
• 関連するPDBエントリー: 4I82 4XY5 4XY6 4ZRF
• 分子名称: Hypothetical Thioesterase Protein SP_1851, COENZYME A (3 entities in total)
• 機能のキーワード: paai thioesterase, hotdog fold, streptococcus pneumoniae, hydrolase
• 由来する生物種: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 124952.33

構造登録者

Khandokar, Y.B.,Srivastava, P.,Forwood, J.K. (登録日: 2015-05-12, 公開日: 2015-05-27, 最終更新日: 2023-09-27)

• 主引用文献: Khandokar, Y.B.,Srivastava, P.,Sarker, S.,Swarbrick, C.M.,Aragao, D.,Cowieson, N.,Forwood, J.K.; Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism.; J.Biol.Chem., 291:1866-1876, 2016; PubMed: 26538563; DOI: 10.1074/jbc.M115.677484

実験手法

X-RAY DIFFRACTION (2.2 Å)