4YR8

Crystal structure of JNK in complex with a regulator protein

Summary for 4YR8

• Entry DOI: 10.2210/pdb4yr8/pdb
• Descriptor: Mitogen-activated protein kinase 8, Dual specificity protein phosphatase 16, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: kinase domain, catalytic domain, transferase-hydrolase complex, transferase/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : P45983 Q9BY84
• Total number of polymer chains: 8
• Total formula weight: 247139.27

Authors

Liu, X.,Wang, J.,Wu, J.W.,Wang, Z.X. (deposition date: 2015-03-14, release date: 2016-03-16, Last modification date: 2023-11-08)

• Primary citation: Liu, X.,Zhang, C.S.,Lu, C.,Lin, S.C.,Wu, J.W.,Wang, Z.X.; A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.; Nat Commun, 7:10879-10879, 2016; PubMed: 26988444; DOI: 10.1038/ncomms10879

Experimental method

X-RAY DIFFRACTION (2.4 Å)