4YOL

Human fibroblast growth factor-1 C16S/A66C/C117A/P134A

Summary for 4YOL

• Entry DOI: 10.2210/pdb4yol/pdb
• Related: 1JQZ 1RG8 2AFG 3FJK 3HOM 4Q9G 4QAL
• Descriptor: Fibroblast growth factor 1, CITRATE ANION, IMIDAZOLE, ... (4 entities in total)
• Functional Keywords: fibroblast growth factor-1, cysteine-free mutant, fgf-1, intramolecular disulfide, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 33998.97

Authors

Xia, X.,Blaber, M. (deposition date: 2015-03-11, release date: 2016-03-16, Last modification date: 2019-02-13)

• Primary citation: Xia, X.,Kumru, O.S.,Blaber, S.I.,Middaugh, C.R.,Li, L.,Ornitz, D.M.,Sutherland, M.A.,Tenorio, C.A.,Blaber, M.; Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.; J.Pharm.Sci., 105:1444-1453, 2016; PubMed: 27019961; DOI: 10.1016/j.xphs.2016.02.010

Experimental method

X-RAY DIFFRACTION (1.97 Å)