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4YKM

Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32W:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution

Summary for 4YKM
Entry DOI10.2210/pdb4ykm/pdb
Related2G7B 4I9S 4RUU 4YBP 4YFP 4YFQ
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsphotoswitchable protein, rhodopsin mimic, retinal isomerization, retinal iminium pka change, protein engineering, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: P29373
Total number of polymer chains2
Total formula weight31848.54
Authors
Nosrati, M.,Geiger, J.H. (deposition date: 2015-03-04, release date: 2016-03-09, Last modification date: 2023-09-27)
Primary citationNosrati, M.,Berbasova, T.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution.
J.Am.Chem.Soc., 138:8802-8808, 2016
Cited by
PubMed: 27310917
DOI: 10.1021/jacs.6b03681
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation

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