4YHZ

Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide

Summary for 4YHZ

• Entry DOI: 10.2210/pdb4yhz/pdb
• Related: 4YHP 4YHY
• Descriptor: Fab Heavy Chain, Fab Light Chain, H3K4me3 peptide, ... (6 entities in total)
• Functional Keywords: antibody, fab, head-to-head dimerization, h3k4me3, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 50149.73

Authors

Hattori, T.,Dementieva, I.S.,Montano, S.P.,Koide, S. (deposition date: 2015-02-27, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Hattori, T.,Lai, D.,Dementieva, I.S.,Montano, S.P.,Kurosawa, K.,Zheng, Y.,Akin, L.R.,Swist-Rosowska, K.M.,Grzybowski, A.T.,Koide, A.,Krajewski, K.,Strahl, B.D.,Kelleher, N.L.,Ruthenburg, A.J.,Koide, S.; Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.; Proc.Natl.Acad.Sci.USA, 113:2092-2097, 2016; PubMed: 26862167; DOI: 10.1073/pnas.1522691113

Experimental method

X-RAY DIFFRACTION (2.304 Å)