4YGY

Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide

Summary for 4YGY

• Entry DOI: 10.2210/pdb4ygy/pdb
• Related: 4YGX 4YH1
• Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, peptidomimetic CTD phospho-Ser5 peptide, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: phosphatase, peptidomimetic, complex, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q9GZU7
• Total number of polymer chains: 4
• Total formula weight: 45714.07

Authors

Mayfield, J.E.,Zhang, Y. (deposition date: 2015-02-26, release date: 2015-09-16, Last modification date: 2015-10-28)

• Primary citation: Mayfield, J.E.,Fan, S.,Wei, S.,Zhang, M.,Li, B.,Ellington, A.D.,Etzkorn, F.A.,Zhang, Y.J.; Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.; Acs Chem.Biol., 10:2405-2414, 2015; PubMed: 26332362; DOI: 10.1021/acschembio.5b00296

Experimental method

X-RAY DIFFRACTION (2.36 Å)