Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human Cellular Retinoic Acid Binding ProteinII in complex with Retinal after 24 h incubation and 1 hour UV irradiation at 1.92 angstrom - 1st cycle

Summary for 4YBU

Related4YBP 2G7B 4I9R 4I9S 4RUU 4EEJ
DescriptorCellular retinoic acid-binding protein 2, RETINAL (3 entities in total)
Functional Keywordsphotoswitchable protein, retinal isomerization, retinal psb, protein engineering, retinal iminium pka change by isomerization, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P29373
Total number of polymer chains1
Total molecular weight15828.18
Nosrati, M.,Geiger, J.H. (deposition date: 2015-02-19, release date: 2016-02-24, Last modification date: 2016-08-03)
Primary citation
Nosrati, M.,Berbasova, T.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution.
J.Am.Chem.Soc., 138:8802-8808, 2016
PubMed: 27310917 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.6b03681
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24230.7%0.8%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution