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4Y24

Complex of human Galectin-1 and TD-139

Summary for 4Y24
Entry DOI10.2210/pdb4y24/pdb
Related4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22
DescriptorGalectin-1, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside (3 entities in total)
Functional Keywordscomplex, galectin-1, tdg, td-139, sugar binding protein
Biological sourceHomo sapiens (Human)
Cellular locationSecreted, extracellular space, extracellular matrix : P09382
Total number of polymer chains2
Total formula weight34959.20
Authors
Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (deposition date: 2015-02-09, release date: 2016-04-27, Last modification date: 2024-03-20)
Primary citationHsieh, T.J.,Lin, H.Y.,Tu, Z.,Lin, T.C.,Wu, S.C.,Tseng, Y.Y.,Liu, F.T.,Hsu, S.T.,Lin, C.H.
Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors.
Sci Rep, 6:29457-29457, 2016
Cited by
PubMed: 27416897
DOI: 10.1038/srep29457
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.32 Å)
Structure validation

218500

數據於2024-04-17公開中

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