4XUM

PPARgamma ligand binding domain in complex with indomethacin

Summary for 4XUM

Entry DOI	10.2210/pdb4xum/pdb
Related	4XTA 4XUH
Descriptor	Peroxisome proliferator-activated receptor gamma, INDOMETHACIN (3 entities in total)
Functional Keywords	ppargamma, nuclear receptor, transcription factor, nsaids, indomethacin, translation
Biological source	Homo sapiens (Human)
Cellular location	Nucleus: P37231
Total number of polymer chains	2
Total formula weight	64543.09
Authors	Puhl, A.C.,Webb, P.,Polikarpov, I. (deposition date: 2015-01-26, release date: 2015-11-04, Last modification date: 2024-02-28)
Primary citation	Puhl, A.C.,Milton, F.A.,Cvoro, A.,Sieglaff, D.H.,Campos, J.C.,Bernardes, A.,Filgueira, C.S.,Lindemann, J.L.,Deng, T.,Neves, F.A.,Polikarpov, I.,Webb, P. Mechanisms of peroxisome proliferator activated receptor gamma regulation by non-steroidal anti-inflammatory drugs. Nucl Recept Signal, 13:e004-e004, 2015 Cited by PubMed: 26445566 DOI: 10.1621/nrs.13004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation