4WHG

Crystal Structure of TR3 LBD in complex with Molecule 3

Summary for 4WHG

Entry DOI	10.2210/pdb4whg/pdb
Related	4re8 4ree 4ref 4whf
Descriptor	Nuclear receptor subfamily 4 group A member 1, GLYCEROL, 1-(3,4,5-trihydroxyphenyl)octan-1-one, ... (4 entities in total)
Functional Keywords	lbd, transcription
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P22736
Total number of polymer chains	2
Total formula weight	58203.39
Authors	Li, F.W.,Cai, Q.X.,Li, A.Z.,Tian, X.Y.,Wang, W.J.,Wang, Y.,Hou, P.P.,Wu, Q.,Lin, T.W. (deposition date: 2014-09-22, release date: 2015-09-09, Last modification date: 2024-03-20)
Primary citation	Wang, W.J.,Wang, Y.,Hou, P.P.,Li, F.W.,Zhou, B.,Chen, H.Z.,Bian, X.L.,Cai, Q.X.,Xing, Y.Z.,He, J.P.,Zhang, H.,Huang, P.Q.,Lin, T.,Wu, Q. Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22:1040-1051, 2015 Cited by PubMed: 26235054 DOI: 10.1016/j.chembiol.2015.06.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation