4V56

Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin.

This is a non-PDB format compatible entry.

Summary for 4V56

• Entry DOI: 10.2210/pdb4v56/pdb
• Related: 2QOV 2QOW 2QOX
• Descriptor: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... (56 entities in total)
• Functional Keywords: rna-protein complex, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, antibiotic resistance, repressor, transcription, transcription regulation, transcription termination, translation regulation, acetylation, trna-binding, methylation, endonuclease, hydrolase, nuclease, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 104
• Total formula weight: 4295842.30

Authors

Borovinskaya, M.A.,Shoji, S.,Holton, J.M.,Fredrick, K.,Cate, J.H.D. (deposition date: 2007-07-21, release date: 2014-07-09, Last modification date: 2023-09-20)

• Primary citation: Borovinskaya, M.A.,Shoji, S.,Holton, J.M.,Fredrick, K.,Cate, J.H.; A steric block in translation caused by the antibiotic spectinomycin.; Acs Chem.Biol., 2:545-552, 2007; PubMed: 17696316; DOI: 10.1021/cb700100n

Experimental method

X-RAY DIFFRACTION (3.93 Å)