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4UHA

Structure of bovine endothelial nitric oxide synthase heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(methyl(2-(methylamino)ethyl)amino)benzonitrile

Summary for 4UHA
Entry DOI10.2210/pdb4uha/pdb
Related4UGZ 4UH0 4UH1 4UH2 4UH3 4UH4 4UH5 4UH6 4UH7 4UH8 4UH9
DescriptorNITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (8 entities in total)
Functional Keywordsoxidoreductase, inhibitor complex
Biological sourceBOS TAURUS (CATTLE)
Total number of polymer chains2
Total formula weight102302.14
Authors
Li, H.,Poulos, T.L. (deposition date: 2015-03-23, release date: 2015-07-15, Last modification date: 2019-01-30)
Primary citationKang, S.,Li, H.,Tang, W.,Martasek, P.,Roman, L.J.,Poulos, T.L.,Silverman, R.B.
2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.
J. Med. Chem., 58:5548-5560, 2015
Cited by
PubMed: 26120733
DOI: 10.1021/acs.jmedchem.5b00573
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

數據於2024-03-27公開中

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