4U7P
Crystal structure of DNMT3A-DNMT3L complex
Summary for 4U7P
Entry DOI | 10.2210/pdb4u7p/pdb |
Related | 4U7T |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3-like, ZINC ION, ... (4 entities in total) |
Functional Keywords | dna methyltransferase, autoinhibitory form, transferase-transferase regulator complex, transferase/transferase regulator |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9Y6K1 Q9UJW3 |
Total number of polymer chains | 2 |
Total formula weight | 78050.64 |
Authors | |
Primary citation | Guo, X.,Wang, L.,Li, J.,Ding, Z.,Xiao, J.,Yin, X.,He, S.,Shi, P.,Dong, L.,Li, G.,Tian, C.,Wang, J.,Cong, Y.,Xu, Y. Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517:640-644, 2015 Cited by PubMed: 25383530DOI: 10.1038/nature13899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.821 Å) |
Structure validation
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